Obesity and thrombotic risk

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Invited Commentary Obesity and thrombotic risk

The link between obesity and thrombotic risk represents an important issue since the prevalence of obesity in adults has increased rapidly in the last decades, especially in Western countries although this is an emerging health issue elsewhere too. Estimates from the WHO indicate that globally there are more than 300 million obese adults. From a physiological point of view, adipose tissue is th...

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Thrombotic risk factors: basic pathophysiology.

Although venous thrombosis has been traditionally associated with stasis and hypercoagulability, arterial thrombosis is mainly associated with heightened platelet reactivity and damage to the vessel wall. Accordingly, classic risk factors for venous and arterial thrombosis are usually considered distinct. Those for the former include cancer, surgery, pregnancy, and estrogens use, whereas risk f...

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Cancer and Thrombotic Risk: The Platelet Paradigm

Hematologic malignancies and solid tumors increase the risk of venous and arterial thrombosis and contribute greatly to patient morbidity and mortality. Thrombosis occurs when the intricate balance of circulating antithrombotic and prothrombotic blood elements are disrupted. In recent years, the interplay between paraneoplastic cells and platelets has become apparent, with a change in platelet ...

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Knowledge and Attitude on Cardiovascular Disease Risk Factors and Their Relationship with Obesity and Biochemical Parameters

Background: According to the high prevalence of cardiovascular diseases (CVDs) in developing countries as well as high treatment expenses for patients and health-care systems, CVDs prevention in such societies has a great importance. One of the most effective strategies is improvement of knowledge and attitude towards the CVDs risk factors. This study aimed to evaluate the knowledge and attitud...

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Obesity and fracture risk.

Obesity and osteoporosis are two common diseases with an increasing prevalence and a high impact on morbidity and mortality. Obese women have always been considered protected against osteoporosis and osteoporotic fractures. However, several recent studies have challenged the widespread belief that obesity is protective against fracture and have suggested that obesity is a risk factor for certai...

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ژورنال

عنوان ژورنال: British Journal of Nutrition

سال: 2010

ISSN: 0007-1145,1475-2662

DOI: 10.1017/s0007114510002849